12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response
نویسندگان
چکیده
منابع مشابه
12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response.
Central obesity is associated with chronic inflammation, insulin resistance, β-cell dysfunction, and endoplasmic reticulum (ER) stress. The 12/15-lipoxygenase enzyme (12/15-LO) promotes inflammation and insulin resistance in adipose and peripheral tissues. Given that obesity is associated with ER stress and 12/15-LO is expressed in adipose tissue, we determined whether 12/15-LO could mediate ER...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2012
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00373.2011